讲座题目：儿童青少年脑结构连接发育规律研究
主讲人：崔再续 研究员
主持人：尹大志 研究员
开始时间：2024-06-20 15:00
讲座地址：普陀校区俊秀楼223报告厅
主办单位：心理与认知科学学院
报告人简介：
崔再续，北京脑科学与类脑研究所，研究员，博士生导师。2011年于安徽大学计算机科学与技术学院获得本科学位，2017年于北京师范大学脑与认知科学研究院获得博士学位，后于美国宾夕法尼亚大学医学院从事博士后研究至2021年。研究内容关注脑结构与功能网络的组织原则及其在儿童青少年阶段的典型及异常发育规律，以第一/通讯作者（含共同）发表研究于Neuron, Nature Communications, Biological Psychiatry, eLife, NeuroImage等期刊。开发的弥散磁共振成像数据处理软件PANDA，下载量已逾20,000次。入选国家高层次海外青年人才项目，北京市科技新星，美国心理科学协会（APS）新星奖（Rising star）。主持科技部科技创新2030-“脑科学与类脑研究”重大项目的青年科学家项目。
报告内容：
Childhood and adolescence are associated with protracted developmental remodeling of cortico-cortical structural connectivity. However, how heterochronous development in white matter structural connectivity spatially and temporally unfolds across the macroscale human connectome remains unknown. Leveraging non-invasive diffusion MRI data from both cross-sectional and longitudinal developmental datasets, we found that structural connectivity development diverges across connectome edges from ages 8.1 to 21.9 years. Specifically, we observed that the structural connectivity development spans from an early childhood increase in connectivity strength in sensorimotor-sensorimotor connections to a late adolescent increase in association-association connection strength. We also observed a critical transtition of neurodevelopmental program at around 15.5 years old. Our findings provide novel description of the spatial variation in the development of structural connectivity across the human connectome.
